Yin Chen Hao Wan (Yin Chen Hao Tang,
Yin Chen Hao Pian, 茵陈蒿汤)
is an ancient Chinese herbal medicine regularly used by Chinese doctors for jaundice in
newborn babies and hepatitis. A common modification of the formula is Yin Zhi Huang
(JaundiclearTM). In 2004,
a USA research in Baylor College of Medicine confirmed
that the herbal remedy can accelerate the clearance of bilirubin (jaundice) and revealed the
molecular pathway that links the formula to jaundice clearance.1
|
|
What does it do?
Yin Chen Hao Tang was originally invented about 2000 years ago
with a composition of 3 herbs: Artemisia capillaris (Yin Chen, Yin Chin), Gardenia jasminoides Ellis
(Zhi Zi), Rheum officinale Baill (Da Huang). Artemisiae is the major herb in the formula
that helps clear the jaundice. It also clears heat and dampness. Gardeniae and Rheum act to enhance
the function of Artemisiae.
In the past 40 years, There have been some modifications of the original Yin Chen Hao Tang recipe.
Often times more herbs are added to the formula to reflect our current understanding on herbology
and supposedly to enhance the action. The recipe we have here (see below) contains 10 herbs and
carries the original name of Yin Chen Hao. The recipe used in the breakthrough study contains one extra
herb, Scutellaria baicalensis Georgi (Huang Qin), and is named as Yin Zhi Huang.1
What does the study find?
Jaundice is the yellowing of the skin and whites of the eyes resulted from the accumulation of
bile pigment bilirubin. In the new study published in the Journal of Clinical Investigation in 20041,
the scientists led by Dr. David Moore were first able to confirm what scientists in China have long
reported, that is, Yin Zhi Huang can significantly enhance the clearance of bilirubin from the serum and
the liver in the animal model. Then, they were able to track down the protein in the
body that mediates this effect of Yin Zhi Huang. The protein is a liver receptor called CAR
(Constitutive androstane receptor), which is a key regulator of the bilirubin clearance pathway.
When CAR is missing in the body, then Yin Zhi Huang can no longer clear bilirubin.
Interestingly, Artemisiae by itself can increase the bilirubin clearance albeit at lower
efficacy.
Surprisingly, the scientists were able to further narrow down a single molecule in Artemisiae
that activates CAR which causes subsequent activation of proteins in the the bilirubin clearance pathway.
The study on Yin Zhi Huang is wonderful and nicely illustrated
both the wisdom a Traditional Chinse medicine could be and how powerful the modern biomedical
research can be in uncovering the mystery surrounding traditional Chinese medicines.
|
What is the formula composition?
A proprietary blend* of
Artemisia capillaris
Gardenia jasminoides Ellis
Rheum officinale Baill
Caulis Bambusae In Taeniam
Radix Isatidis
Cortex Phellodendri
Radix Bupleuri
Adix Curcumae
Poria
Pericarpium Citri Reticulatae
|
(Yin Chen, Yin Chin)
(Zhi Zi)
(Da Huang)
(Zhu Ru)
(Ban Lan Gen)
(Huang Bo)
(Chai Hu)
(Yu Jin)
(Fu Ling)
(Chen Pi)
|
|
*Yin Chen Hao Wan (Pian) is made of 100% pure authentic Chinese
herbs of highest qualities.
Traditional preparation procedures are combined with modern pharmaceutical processes to extract the active
ingredients from the herbs and to further concentrate them into pills or tablets. It is produced in the certified GMP facility of the famous Shanghai
No. 1 Traditional Chinese Medicine Factory (Guang Ci Tang) and is imported to USA in accordance with the FDA guidelines.
It contains no pharmaceuticals,
no artificial colors, and no sugar. Heavy metals are within or well beyond the standards set by US Pharmacopeia. Additionally,
Plum Flower only uses its own brand unsulfured herbs for production.
|
What is Available?
One top Chinese herbs brand:
Guang Ci Tang (learn more):
40 grams in 200 tablets or 200 pills per bottle.
|
Yin Zhi Huang is produced by ActiveHerb under the name of JaundiclearTM. The product is made
in USA. Learn More
|
How do I use it?
Take 5 to 7 pills or tablets three times daily
For children, dose should be reduced accordingly to the weight.
|
Use Discrimination
|
Side Effects
Yin Chen Hao Wan has been safely used with few adverse effects
when used as directed.
|
Cautious Notes
1. Not suitable for jaundice with cold feeling of the body.
2. Keep out of reach of children.
|
References
1. Huang W, Zhang J, Moore DD. A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR.
J Clin Invest. 2004 Jan;113(1):137-43.
|
